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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cathepsin S

UniprotKB/SwissProt ID: O70370 (O70370)

Gene Name: Ctss

Organism: Mus musculus (Mouse)

Function: Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Lysosome. Secreted. Cytoplasmic vesicle, phagosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR038765 Papain-like_cys_pep_sf
IPR025661 Pept_asp_AS
IPR000169 Pept_cys_AS
IPR025660 Pept_his_AS
IPR013128 Peptidase_C1A
IPR000668 Peptidase_C1A_C
IPR039417 Peptidase_C1A_papain-like
IPR013201 Prot_inhib_I29

The S-nitrosylation sites of O70370

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 281 YKSGVYDDPS C TGNVNHGVLV  CCCCCHHHHH H HHHHHHHHHH  7.41% 22178444
19483679
2 329 IRMARNNKNH C GIASYCSYPE  CCCCCHHHHH H HHHHHHHHHH  6.19% 22178444
19483679
3 335 NKNHCGIASY C SYPEI-----  CCCCCHHHHH H HHHHHHHHHH  2.66% 22178444
19483679