Protein Name:
NEDD8-activating enzyme E1 catalytic subunit
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UniprotKB/SwissProt ID: O65041 (O65041)
Gene Name:
ECR1
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalytic subunit of the dimeric ECR1-AXR1 E1 enzyme. E1 activates NEDD8/RUB1 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-ECR1 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of RCE1 (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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