Protein Name:
mRNA-capping enzyme
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UniprotKB/SwissProt ID: O60942 (O60942)
Gene Name:
RNGTT
Organism: Homo sapiens (Human)
Function: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O60942
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
13 |
HNKIPPRWLN C PRRGQPVAGR |
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| 2 |
375 |
IKFNSQPVGD C DFNVRLQCIE |
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| 3 |
419 |
SVRNKPFFDI C TSRKLLEGNF |
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