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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: DNA/RNA-binding protein KIN17

UniprotKB/SwissProt ID: O60870 (O60870)

Gene Name: KIN

Organism: Homo sapiens (Human)

Function: Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo (By similarity). Binds via its C-terminal domain to RNA in vitro

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR056767 C2H2-Znf_KIN17
IPR019447 DNA/RNA-bd_Kin17_WH-like_dom
IPR037321 KIN17-like
IPR038254 KIN17_WH-like_sf
IPR041330 KN17_SH3
IPR041995 KOW_KIN17
IPR014722 Rib_uL2_dom2
IPR036236 Znf_C2H2_sf

The S-nitrosylation sites of O60870

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 212 KVTFNLSKGA C SSSGATSSKS