Protein Name:
UDP-glucose 6-dehydrogenase
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UniprotKB/SwissProt ID: O60701 (O60701)
Gene Name:
UGDH
Organism: Homo sapiens (Human)
Function: Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans (PubMed:21502315, PubMed:21961565, PubMed:22123821, PubMed:23106432, PubMed:25478983, PubMed:27966912, PubMed:30420606, PubMed:30457329). Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). Required for proper brain and neuronal development (PubMed:32001716)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O60701
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
112 |
RAADLKYIEA C ARRIVQNSNG |
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| 2 |
196 |
PEGQRAVQAL C AVYEHWVPRE |
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| 3 |
241 |
ISSINSISAL C EATGADVEEV |
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| 4 |
276 |
LKASVGFGGS C FQKDVLNLVY |
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| 5 |
288 |
QKDVLNLVYL C EALNLPEVAR |
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