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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Vinexin

UniprotKB/SwissProt ID: O60504 (O60504)

Gene Name: SORBS3

Organism: Homo sapiens (Human)

Function: Vinexin alpha isoform promotes up-regulation of actin stress fiber formation. Vinexin beta isoform plays a role in cell spreading and enhances the activation of JNK/SAPK in response to EGF stimulation by using its third SH3 domain

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell junction. Cytoplasm, cytoskeleton. Cell junction. Nucleus. Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050384 Endophilin_SH3RF
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR003127 SoHo_dom
IPR035609 Vinexin_SH3_1
IPR035608 Vinexin_SH3_2
IPR035607 Vinexin_SH3_3

The S-nitrosylation sites of O60504

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 521 QVSREPRLRL C DDGPQLPTSP   
2 645 EGDRVDVMQQ C DDGWFVGVSR