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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Periplakin

UniprotKB/SwissProt ID: O60437 (O60437)

Gene Name: PPL

Organism: Homo sapiens (Human)

Function: Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell junction, desmosome. Cytoplasm, cytoskeleton. Cell membrane. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR041615 Desmoplakin_SH3
IPR043197 Plakin
IPR035915 Plakin_repeat_sf
IPR001101 Plectin_repeat
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR055419 Spectrin_PEPL/EVPL

The S-nitrosylation sites of O60437

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1265 IVDKTRLIER C DLEIYQLKKE   
2 311 DWKEYLNLLI C EESHLKYMED   
3 449 AGNKLIAPAV C FVIPPTDPEA   
4 694 STLASRFQEH C PDLERQEAEV   
5 788 ASREQEVQKI C ANSQQYQQAV