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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Zinc finger C3H1 domain-containing protein

UniprotKB/SwissProt ID: O60293 (O60293)

Gene Name: ZFC3H1

Organism: Homo sapiens (Human)

Function: Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003107 HAT
IPR019607 Putative_zinc-finger_domain
IPR039278 Red1
IPR011990 TPR-like_helical_dom_sf

The S-nitrosylation sites of O60293

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 220 KQNYSSKNEN C VEETFEDLLL