Protein Name:
C-Jun-amino-terminal kinase-interacting protein 4
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UniprotKB/SwissProt ID: O60271 (O60271)
Gene Name:
SPAG9
Organism: Homo sapiens (Human)
Function: The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module (PubMed:14743216). Regulates lysosomal positioning by acting as an adapter protein which links PIP4P1-positive lysosomes to the dynein-dynactin complex (PubMed:29146937). Assists PIKFYVE selective functionality in microtubule-based endosome-to-TGN trafficking (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, perinuclear region. Lysosome membrane. Cytoplasmic vesicle, secretory vesicle, acrosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O60271
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
443 |
DLIAKVDELT C EKDVLQGELE |
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