Protein Name:
Mediator of RNA polymerase II transcription subunit 14
|
UniprotKB/SwissProt ID: O60244 (O60244)
Gene Name:
MED14
Organism: Homo sapiens (Human)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of O60244
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
172 |
TTGSYPRLPT C IRDKIIPPDP |
|
|
|
| 2 |
635 |
SKKTKRAGEM C AFNKVLAHFV |
|
|
|
| 3 |
779 |
DWNSIARLYE C VLEFARSLPD |
|
|
|
|
