Protein Name:
Glyceraldehyde-3-phosphate dehydrogenase
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UniprotKB/SwissProt ID: O57672 (O57672)
Gene Name:
GAPDH
Organism: Meleagris gallopavo (Wild turkey)
Function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity). Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O57672
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
61 |
KSLKIVSNAL C TTNCLAPLAK |
CCEEEEECCC E ECHHHCCCCC |
4.02% |
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