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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: mRNA-capping enzyme

UniprotKB/SwissProt ID: O55236 (O55236)

Gene Name: Rngtt

Organism: Mus musculus (Mouse)

Function: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000340 Dual-sp_phosphatase_cat-dom
IPR017074 mRNA_cap_enz_bifunc
IPR001339 mRNA_cap_enzyme_adenylation
IPR013846 mRNA_cap_enzyme_C
IPR051029 mRNA_Capping_Enz/RNA_Phosphat
IPR012340 NA-bd_OB-fold
IPR029021 Prot-tyrosine_phosphatase-like
IPR016130 Tyr_Pase_AS
IPR000387 Tyr_Pase_dom
IPR020422 TYR_PHOSPHATASE_DUAL_dom