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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Acyl-coenzyme A thioesterase 1

UniprotKB/SwissProt ID: O55137 (O55137)

Gene Name: Acot1

Organism: Mus musculus (Mouse)

Function: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR029058 AB_hydrolase_fold
IPR016662 Acyl-CoA_thioEstase_long-chain
IPR014940 BAAT_C
IPR006862 Thio_Ohase/aa_AcTrfase
IPR042490 Thio_Ohase/BAAT_N

The S-nitrosylation sites of O55137

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 14 TLNLEPSGRS C WDEPLSIAVR  CCCCCCCCCC C CCCCCCCCEE  5.24% 21278135
2 412 TFFHKQLGSE C LHVSPKI---  CCCCCCCCCC C CCCCCCCCEE  3.22%