Protein Name:
Contactin-associated protein 1
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UniprotKB/SwissProt ID: O54991 (O54991)
Gene Name:
Cntnap1
Organism: Mus musculus (Mouse)
Function: Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons (PubMed:25378149). Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells (PubMed:11395000, PubMed:25378149)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane. Cell junction, paranodal septate junction
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O54991
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1210 |
QRYNTPGFSG C LSGVRFNNVA |
CCHHHHHHHH H HHHHHCCCCC |
2.37% |
24895380
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| 2 |
1251 |
RVQGELSESN C GAMPRLVSEV |
CCHHHHHHHH H HHHHHCCCCC |
5.24% |
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