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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: AP-3 complex subunit delta-1

UniprotKB/SwissProt ID: O54774 (O54774)

Gene Name: Ap3d1

Organism: Mus musculus (Mouse)

Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes (By similarity). Involved in process of CD8+ T-cell and NK cell degranulation (By similarity). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (PubMed:21998198)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Golgi apparatus membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR017105 AP3_complex_dsu
IPR010474 AP3D_dom_metazoa
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N

The S-nitrosylation sites of O54774

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 39 KEDEAKYISQ C IDEIKQELKQ   
2 574 ADLEVQERAS C ILQLVKHVQK