UniprotKB/SwissProt ID: O49839 (O49839)
Gene Name:
PBL2
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in disease resistance signaling (PubMed:20413097, PubMed:23951354, PubMed:26355215). Contributes to pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) signaling and defense responses downstream of FLS2 (PubMed:20413097). Acts as a BIK1 decoy and enables Xanthomonas campestris AvrAC/XopAC detection; X.campestris effector AvrAC/XopAC-mediated uridylylation promotes the formation of a complex with RKS1 and RPP13L4/ZAR1 which, in turn, activates effector-triggered immunity (ETI) against X.campestris (PubMed:23951354, PubMed:26355215, PubMed:30948526). Promotes, when uridylylated by AvrAC/XopAC, the release of ADP from the inactive RKS1-ZAR1 complex, thus activating the resistosome (PubMed:30948526)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Nucleus
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