Protein Name:
AP-1 complex subunit gamma-1
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UniprotKB/SwissProt ID: O43747 (O43747)
Gene Name:
AP1G1
Organism: Homo sapiens (Human)
Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes (PubMed:15758025)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Membrane, clathrin-coated pit
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O43747
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
160 |
NSYLRKKAAL C AVHVIRKVPE |
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| 2 |
392 |
MKELLYFLDS C EPEFKADCAS |
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| 3 |
400 |
DSCEPEFKAD C ASGIFLAAEK |
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| 4 |
539 |
AIMKLSTRFT C TVNRIKKVVS |
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