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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: A-kinase anchor protein 7 isoforms alpha and beta

UniprotKB/SwissProt ID: O43687 (O43687)

Gene Name: AKAP7

Organism: Homo sapiens (Human)

Function: Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Lateral cell membrane. Apical cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR052641 AKAP7_isoform_gamma
IPR019511 AKAP7_RI-RII-bd_dom