Protein Name:
Pleiotropic regulator 1
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UniprotKB/SwissProt ID: O43660 (O43660)
Gene Name:
PLRG1
Organism: Homo sapiens (Human)
Function: Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28076346, PubMed:28502770). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing (PubMed:11101529, PubMed:11544257). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus speckle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O43660
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
209 |
VISGHLGWVR C IAVEPGNQWF |
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| 2 |
264 |
VSTRSPYLFS C GEDKQVKCWD |
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| 3 |
272 |
FSCGEDKQVK C WDLEYNKVIR |
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| 4 |
338 |
GHTNAVATVR C QAAEPQIITG |
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| 5 |
468 |
SLDSESGIFA C AFDQSESRLL |
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