Protein Name:
Bcl-2-like protein 11
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UniprotKB/SwissProt ID: O43521 (O43521)
Gene Name:
BCL2L11
Organism: Homo sapiens (Human)
Function: Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endomembrane system. Mitochondrion. Mitochondrion. Mitochondrion. Mitochondrion
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O43521
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
12 |
AKQPSDVSSE C DREGRQLQPA |
CCCCCCCCCH H CCCCCCCCCC |
6.89% |
24105792
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