Protein Name:
Tumor necrosis factor ligand superfamily member 12
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UniprotKB/SwissProt ID: O43508 (O43508)
Gene Name:
TNFSF12
Organism: Homo sapiens (Human)
Function: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Secreted. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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