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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Maltase-glucoamylase

UniprotKB/SwissProt ID: O43451 (O43451)

Gene Name: MGAM

Organism: Homo sapiens (Human)

Function: Alpha-(1,4) exo-glucosidase involved in breakdown of dietary starch oligosaccharides in small intestine. Cleaves the non-reducing alpha-(1,4)-linked glucose residue in linear dextrins with retention of anomeric center stereochemistry (PubMed:12547908, PubMed:18036614, PubMed:18356321, PubMed:22058037, PubMed:27480812). Mainly hydrolyzes short length oligomaltoses having two to seven glucose residues (PubMed:12547908, PubMed:18036614, PubMed:18356321, PubMed:22058037, PubMed:27480812). Can cleave alpha-(1,2), alpha-(1,3) and alpha-(1,6) glycosidic linkages with lower efficiency, whereas beta glycosidic linkages are usually not hydrolyzed (PubMed:27480812)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Apical cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011013 Gal_mutarotase_sf_dom
IPR030458 Glyco_hydro_31_AS
IPR048395 Glyco_hydro_31_C
IPR030459 Glyco_hydro_31_CS
IPR025887 Glyco_hydro_31_N_dom
IPR000322 Glyco_hydro_31_TIM
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR017957 P_trefoil_CS
IPR000519 P_trefoil_dom
IPR044913 P_trefoil_dom_sf