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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: 52 kDa repressor of the inhibitor of the protein kinase

UniprotKB/SwissProt ID: O43422 (O43422)

Gene Name: THAP12

Organism: Homo sapiens (Human)

Function: Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR025398 DUF4371
IPR008906 HATC_C_dom
IPR052958 IFN-induced_PKR_regulator
IPR012337 RNaseH-like_sf
IPR006612 THAP_Znf

The S-nitrosylation sites of O43422

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 644 NPDTLSAELH C WRIKWKHRGK