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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: U4/U6 small nuclear ribonucleoprotein Prp4

UniprotKB/SwissProt ID: O43172 (O43172)

Gene Name: PRPF4

Organism: Homo sapiens (Human)

Function: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Nucleus speckle

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR020472 G-protein_beta_WD-40_rep
IPR014906 PRP4-like
IPR036285 PRP4-like_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR019775 WD40_repeat_CS
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt

The S-nitrosylation sites of O43172

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 263 GLCKLWSVPD C NLLHTLRGHN   
2 299 LDPKDVNLAS C AADGSVKLWS   
3 342 HPSGRFLGTT C YDRSWRLWDL   
4 431 HIATGSGDNT C KVWDLRQRRC   
5 441 CKVWDLRQRR C VYTIPAHQNL   
6 510 ISSDGQLIAT C SYDRTFKLWM