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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Monoglyceride lipase

UniprotKB/SwissProt ID: O35678 (O35678)

Gene Name: Mgll

Organism: Mus musculus (Mouse)

Function: Converts monoacylglycerides to free fatty acids and glycerol (PubMed:17700715, PubMed:18096503, PubMed:19029917, PubMed:20554061, PubMed:20729846, PubMed:21454566, PubMed:9341166). Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:17700715, PubMed:18096503, PubMed:19029917, PubMed:20554061, PubMed:20729846, PubMed:21454566, PubMed:9341166). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000073 AB_hydrolase_1
IPR029058 AB_hydrolase_fold
IPR022742 Hydrolase_4
IPR051044 MAG_DAG_Lipase

The S-nitrosylation sites of O35678

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 32 LVNADGQYLF C RYWKPSGTPK  CCCCCCCCCC C CCCCHHHCCC  2.77% 21278135