Protein Name:
Vesicular inhibitory amino acid transporter
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UniprotKB/SwissProt ID: O35633 (O35633)
Gene Name:
Slc32a1
Organism: Mus musculus (Mouse)
Function: Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals (PubMed:16701208, PubMed:26912364, PubMed:27601664, PubMed:9395291). The transport is equally dependent on the chemical and electrical components of the proton gradient (PubMed:27601664, PubMed:9395291). May also transport beta-alanine (By similarity). Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake (PubMed:27601664)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasmic vesicle membrane. Presynapse
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR013057
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AA_transpt_TM |
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The S-nitrosylation sites of O35633
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
70 |
MDILKSEGEP C GDEGAEAPVE |
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