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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: H(+)/Cl(-) exchange transporter 6

UniprotKB/SwissProt ID: O35454 (O35454)

Gene Name: Clcn6

Organism: Mus musculus (Mouse)

Function: Voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the late endosome lumen. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Late endosome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000644 CBS_dom
IPR046342 CBS_dom_sf
IPR051280 Cl-channel/antiporter
IPR014743 Cl-channel_core
IPR002248 Cl_channel-6
IPR001807 ClC