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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Acyloxyacyl hydrolase

UniprotKB/SwissProt ID: O18823 (O18823)

Gene Name: AOAH

Organism: Oryctolagus cuniculus (Rabbit)

Function: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides (LPS). By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted. Cytoplasmic vesicle

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR039676 AOAH
IPR048593 AOAH_Saposin_N
IPR001087 GDSL
IPR011001 Saposin-like
IPR008139 SaposinB_dom
IPR036514 SGNH_hydro_sf