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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Branched-chain-amino-acid aminotransferase, mitochondrial

UniprotKB/SwissProt ID: O15382 (O15382)

Gene Name: BCAT2

Organism: Homo sapiens (Human)

Function: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine (PubMed:17050531, PubMed:25653144, PubMed:8702755). May also function as a transporter of branched chain alpha-keto acids (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001544 Aminotrans_IV
IPR018300 Aminotrans_IV_CS
IPR036038 Aminotransferase-like
IPR005786 B_amino_transII
IPR043132 BCAT-like_C
IPR043131 BCAT-like_N
IPR033939 BCAT_family

The S-nitrosylation sites of O15382

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 135 DRMLRSAMRL C LPSFDKLELL  CCHHHHHHHH H HHHHCCCHHH  3.56% 25040305
2 147 PSFDKLELLE C IRRLIEVDKD  CCHHHHHHHH H HHHHCCCHHH  2.71%
3 342 VREVFGSGTA C QVCPVHRILY  CCHHHHHHHH H HHHHCCCHHH  2.9% 19483679
4 345 VFGSGTACQV C PVHRILYKDR  CCHHHHHHHH H HHHHCCCHHH  0.89% 19483679