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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Laminin subunit alpha-5

UniprotKB/SwissProt ID: O15230 (O15230)

Gene Name: LAMA5

Organism: Homo sapiens (Human)

Function: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a role in the regulation of skeletogenesis, through a mechanism that involves integrin-mediated signaling and PTK2B/PYK2 (PubMed:33242826)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR050440 Laminin/Netrin_ECM
IPR009254 Laminin_aI
IPR010307 Laminin_dom_II
IPR001791 Laminin_G
IPR000034 Laminin_IV
IPR008211 Laminin_N
IPR002049 LE_dom
IPR056863 LMN_ATRN_NET-like_EGF
IPR001368 TNFR/NGFR_Cys_rich_reg

The S-nitrosylation sites of O15230

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 3172 LYYRASPDGL C QVSLQQGRVS