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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Granule associated Rac and RHOG effector protein 1

UniprotKB/SwissProt ID: O15063 (O15063)

Gene Name: GARRE1

Organism: Homo sapiens (Human)

Function: Acts as an effector of RAC1 (PubMed:31871319). Associates with CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation (PubMed:29395067). May also play a role in miRNA silencing machinery (PubMed:29395067)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, P-body

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR031813 DUF4745
IPR043385 GARRE1

The S-nitrosylation sites of O15063

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 455 RIVVQVPSTW C LKEDPATMSL