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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Synemin

UniprotKB/SwissProt ID: O15061 (O15061)

Gene Name: SYNM

Organism: Homo sapiens (Human)

Function: Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteromeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteromeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cell junction, adherens junction

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR030634 SYNM

The S-nitrosylation sites of O15061

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1196 EVIFLGPAPA C PEAWGSPEPG   
2 230 RLQAEEETRL C AQEAEALRRE