Protein Name:
Zinc finger protein 609
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UniprotKB/SwissProt ID: O15014 (O15014)
Gene Name:
ZNF609
Organism: Homo sapiens (Human)
Function: Transcription factor, which activates RAG1, and possibly RAG2, transcription. Through the regulation of RAG1/2 expression, may regulate thymocyte maturation. Along with NIPBL and the multiprotein complex Integrator, promotes cortical neuron migration during brain development by regulating the transcription of crucial genes in this process. Preferentially binds promoters containing paused RNA polymerase II. Up-regulates the expression of SEMA3A, NRP1, PLXND1 and GABBR2 genes, among others Involved in the regulation of myoblast proliferation during myogenesis
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O15014
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
178 |
KKERSEGVGT C SEKDPGVLQP |
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