Protein Name:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
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UniprotKB/SwissProt ID: O14983 (O14983)
Gene Name:
ATP2A1
Organism: Homo sapiens (Human)
Function: Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (By similarity). Contributes to calcium sequestration involved in muscular excitation/contraction (PubMed:10914677)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O14983
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
344 |
RSLPSVETLG C TSVICSDKTG |
CCCCCCCCHH H HHHHHCCCCC |
2.63% |
10493809
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| 2 |
349 |
VETLGCTSVI C SDKTGTLTTN |
CCCCCCCCHH H HHHHHCCCCC |
3.95% |
10493809
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