Protein Name:
Heterogeneous nuclear ribonucleoprotein D-like
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UniprotKB/SwissProt ID: O14979 (O14979)
Gene Name:
HNRNPDL
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O14979
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
177 |
YLSRFGEVVD C TIKTDPVTGR |
CCCCCCHHCC C CCCCCCCCCH |
2.61% |
22178444
2212679
20140087
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| 2 |
277 |
DTKTNERRGF C FITYTDEEPV |
CCCCCCHHCC C CCCCCCCCCH |
2.41% |
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| 3 |
303 |
SRYHQIGSGK C EIKVAQPKEV |
CCCCCCHHCC C CCCCCCCCCH |
8.14% |
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