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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Transcription regulator protein BACH1

UniprotKB/SwissProt ID: O14867 (O14867)

Gene Name: BACH1

Organism: Homo sapiens (Human)

Function: Transcriptional regulator that acts as a repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordinating transcription activation and repression by MAFK (By similarity). Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (PubMed:24035498)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000210 BTB/POZ_dom
IPR004827 bZIP
IPR043321 bZIP_BACH
IPR004826 bZIP_Maf
IPR046347 bZIP_sf
IPR011333 SKP1/BTB/POZ_sf
IPR008917 TF_DNA-bd_sf
IPR050457 ZnFinger_BTB_dom_contain

The S-nitrosylation sites of O14867

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 435 SEQISQKRSE C PWLGIRISES   
2 621 GETKQNLTGL C QKVCKEAALS