Protein Name:
Ras-specific guanine nucleotide-releasing factor 2
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UniprotKB/SwissProt ID: O14827 (O14827)
Gene Name:
RASGRF2
Organism: Homo sapiens (Human)
Function: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cell membrane. Endoplasmic reticulum membrane
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Graphical Visualization of S-nitrosylation Sites:
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