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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tripeptidyl-peptidase 1

UniprotKB/SwissProt ID: O14773 (O14773)

Gene Name: TPP1

Organism: Homo sapiens (Human)

Function: Lysosomal serine protease with tripeptidyl-peptidase I activity (PubMed:11054422, PubMed:19038966, PubMed:19038967). May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases (PubMed:11054422, PubMed:19038966, PubMed:19038967). Requires substrates with an unsubstituted N-terminus (PubMed:19038966)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Lysosome. Melanosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000209 Peptidase_S8/S53_dom
IPR036852 Peptidase_S8/S53_dom_sf
IPR015366 S53_propep
IPR030400 Sedolisin_dom
IPR050819 Tripeptidyl-peptidase_I