Protein Name:
AP-3 complex subunit delta-1
|
UniprotKB/SwissProt ID: O14617 (O14617)
Gene Name:
AP3D1
Organism: Homo sapiens (Human)
Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation (PubMed:26744459). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Golgi apparatus membrane
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of O14617
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1103 |
HFSVVERVDS C ASMYSRSIQG |
|
|
|
| 2 |
1133 |
GENSVSVDGK C SDSTLLSNLL |
|
|
|
| 3 |
137 |
DTGVALTGLS C FVTPDLARDL |
|
|
|
| 4 |
208 |
GVQSAAVNVI C ELARRNPKNY |
|
|
|
| 5 |
574 |
ADLEVQERAS C ILQLVKHIQK |
|
|
|
|
