Protein Name:
Peroxiredoxin-4
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UniprotKB/SwissProt ID: O08807 (O08807)
Gene Name:
Prdx4
Organism: Mus musculus (Mouse)
Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events (PubMed:11229364). Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Endoplasmic reticulum
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O08807
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
151 |
FKSINTEVVA C SVDSQFTHLA |
CCCHHHHCCC C CCCHHHHHHH |
2.48% |
20925432
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| 2 |
54 |
DERFRTRENE C HFYAGGQVYP |
CCCHHHHCCC C CCCHHHHHHH |
3.97% |
22178444
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