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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Microsomal triglyceride transfer protein large subunit

UniprotKB/SwissProt ID: O08601 (O08601)

Gene Name: Mttp

Organism: Mus musculus (Mouse)

Function: Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:15897609, PubMed:16478722, PubMed:18502767, PubMed:33168624). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:10713055, PubMed:17635917, PubMed:18502767, PubMed:33168624, PubMed:9502759). May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins (PubMed:18502767) Critical for the development of natural killer T (NKT) cells (PubMed:17312007). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:17635917)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum. Endoplasmic reticulum. Golgi apparatus. Endoplasmic reticulum. Golgi apparatus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR015819 Lipid_transp_b-sht_shell
IPR011030 Lipovitellin_superhlx_dom
IPR045811 MTP_lip-bd
IPR039988 MTTP
IPR015816 Vitellinogen_b-sht_N
IPR001747 Vitellogenin_N