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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Serine/threonine-protein phosphatase PP2A-5 catalytic subunit

UniprotKB/SwissProt ID: O04951 (O04951)

Gene Name: PP2A5

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Associates with the serine/threonine-protein phosphatase PP2A regulatory subunits A and B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins (PubMed:25489022). Involved in the positive regulation of salt stress responses. May function by increasing chloride channel activities on vacuolar membranes (PubMed:27676158)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Peroxisome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR047129 PPA2-like
IPR006186 Ser/Thr-sp_prot-phosphatase

The S-nitrosylation sites of O04951

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 194 IQEVPHEGPM C DLLWSDPDDR