\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
UniprotKB/SwissProt ID: O00750 (O00750)

Gene Name: PIK3C2B

Organism: Homo sapiens (Human)

Function: Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns (PubMed:10805725, PubMed:11533253, PubMed:9830063). Does not phosphorylate PtdIns(4,5)P2 (PubMed:9830063). May be involved in EGF and PDGF signaling cascades (PubMed:10805725)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Microsome. Cell membrane. Cytoplasm, cytosol. Nucleus. Endoplasmic reticulum

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016024 ARM-type_fold
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR036940 PI3/4_kinase_cat_sf
IPR018936 PI3/4_kinase_CS
IPR002420 PI3K-type_C2_dom
IPR001263 PI3K_accessory_dom
IPR042236 PI3K_accessory_sf
IPR000341 PI3K_Ras-bd_dom
IPR015433 PI_Kinase
IPR001683 PX_dom
IPR036871 PX_dom_sf
IPR042134 PX_PI3K_C2_beta
IPR029071 Ubiquitin-like_domsf
The S-nitrosylation sites of O00750
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1054 LLVKGIVPRD C SYFNSNAVPL   
2 151 SPGPGDIEGS C KKLSPPPLPP