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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein Wnt-10b

UniprotKB/SwissProt ID: O00744 (O00744)

Gene Name: WNT10B

Organism: Homo sapiens (Human)

Function: Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically activates canonical Wnt/beta-catenin signaling and thus triggers beta-catenin/LEF/TCF-mediated transcriptional programs. Involved in signaling networks controlling stemness, pluripotency and cell fate decisions. Acts in the immune system, mammary gland, adipose tissue, bone and skin

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix. Secreted

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR005817 Wnt
IPR013302 Wnt10
IPR043158 Wnt_C
IPR018161 Wnt_CS