UniprotKB/SwissProt ID: O00585 (O00585)
Gene Name:
CCL21
Organism: Homo sapiens (Human)
Function: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted
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