Protein Name:
U3 small nucleolar ribonucleoprotein protein MPP10
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UniprotKB/SwissProt ID: O00566 (O00566)
Gene Name:
MPHOSPH10
Organism: Homo sapiens (Human)
Function: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus, nucleolus. Chromosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O00566
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
27 |
EVGKATGRPE C FLTIQEGLAS |
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