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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

UniprotKB/SwissProt ID: O00469 (O00469)

Gene Name: PLOD2

Organism: Homo sapiens (Human)

Function: Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Rough endoplasmic reticulum membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050757 Collagen_mod_GT25
IPR044861 IPNS-like_FE2OG_OXY
IPR029044 Nucleotide-diphossugar_trans
IPR005123 Oxoglu/Fe-dep_dioxygenase_dom
IPR006620 Pro_4_hyd_alph
IPR001006 Procol_lys_dOase

The S-nitrosylation sites of O00469

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 562 IFTENIVEQP C PDVFWFPIFS   
2 576 FWFPIFSEKA C DELVEEMEHY