Protein Name:
TNF receptor-associated factor 5
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UniprotKB/SwissProt ID: O00463 (O00463)
Gene Name:
TRAF5
Organism: Homo sapiens (Human)
Function: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytosol
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O00463
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
161 |
KDLKEHLSAS C QFRKEKCLYC |
CCCCCCCCCC C CEEEECCCCC |
4.42% |
24105792
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