Protein Name:
AP-3 complex subunit beta-1
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UniprotKB/SwissProt ID: O00203 (O00203)
Gene Name:
AP3B1
Organism: Homo sapiens (Human)
Function: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasmic vesicle, clathrin-coated vesicle membrane. Golgi apparatus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O00203
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
215 |
GSVVMAFEEV C PDRIDLIHKN |
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| 2 |
507 |
ASILWLIGEN C ERVPKIAPDV |
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| 3 |
893 |
AAHYFFPRQP C IFGDKMVSIQ |
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