Protein Name:
Ras-related protein Rab-27B
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UniprotKB/SwissProt ID: O00194 (O00194)
Gene Name:
RAB27B
Organism: Homo sapiens (Human)
Function: Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381). Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (PubMed:21775604). May be involved in targeting uroplakins to urothelial apical membranes (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane. Late endosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of O00194
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
123 |
WMSQLQANAY C ENPDIVLIGN |
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